Who Can Benefit from the New U-200 Insulin?

Who Can Benefit from the New U-200 Insulin? The Food and Drug administration (FDA)  recently approved a new 200 unit/mL formulation of Eli Lilly and Company’s pre-filled pen containing insulin lispro (Humalog U-200 KwikPen) for the improvement of glycemic control in patients with type 1 and type 2 diabetes. The new meal time insulin joins other insulin formulations that are not U-100 such as regular...

Is a Cheaper, Off-Label Drug Better for Diabetic Eye Disease?

Is a Cheaper, Off-Label Drug Better for Diabetic Eye Disease? Genentech is a biotech company based in South San Francisco, Ca., and is a member of the Roche Group. The company has the distinction of having two medicines being used for the treatment of diabetic retinopathy. One of these drugs, Lucentis (ranibizumab), was approved back in February to be used in the treatment of diabetes retinopathy for patients with...

GLP-1 Agonist Use in Type 1 Diabetes

GLP-1 Agonist Use in Type 1 Diabetes For those who have type 1 diabetes as well as those who help treat it, it goes without saying that managing type 1 diabetes is very complex and can be frustrating. However, every enterprising type 1 that I work with will look at every treatment angle possible to help reduce blood glucose, hypoglycemia, and weight gain. The term “off-label” does not scare...

New Heart Concerns for Existing Class of Type 2 Medications

New Heart Concerns for Existing Class of Type 2 Medications On April14, the Food & Drug Administration (FDA) panel reviewed the cardiovascular profile of saxagliptin (Onglyza by  AstraZeneca), approved in 2009, and alogliptin (Nesina by Takeda), approved in 2013. Both medications are members of a class known as DPP-4 inhibitors that includes sitagliptin (Januvia), and linagliptin (Tradjenta). The panel has...

A New Long-Acting Insulin Option

A New Long-Acting Insulin Option The FDA has recently approved Toujeo (insulin glargine injection), which is a long-acting insulin containing 300 Units/mL of insulin glargine.  This insulin product comes in a 1.5ml pen that contains 450 units. Toujeo, a basal insulin, is approved for the improvement of glycemic control in adults with type 1 and type 2 diabetes. Toujeo Solostar, a...

A New Treatment for Diabetic Retinopathy

A New Treatment for Diabetic Retinopathy Diabetic retinopathy, a complication of diabetes, has been treated by laser treatment (photocoagulation) as well as surgical removal of the vitreous gel (vitrectomy). In February, the Food and Drug Administration (FDA) approved the drug Lucentis, (ranibizumab), an intravitreal injection, to be used in the treatment of diabetes retinopathy for patients with...